Table of experimentally solved CCP modules (23/10/2009) [ PDF ]
Table of residue lengths of CCP module domain boundaries and inter-CCP module linkers in RCA proteins [ PDF ]
Table of intermodular tilt, twist and skew angles for all solved CCP bimodules and larger fragments [ PDF ]
Table of buried surface area for CCP bimodules [ PDF ]
Table of predicted structural effects of factor H disease-associated sequence variants [ PDF ]
The molecular architectures of the set of human CCP-module containing proteins are taken from SMART [Schultz et al., 1998, Letunic et al., 2002]
and the CCP modules are numbered according to SMART annotations (NOTE: SMART did not detect the following modules: CR2~08, FHR3~05, FHR4~05 and FHR5~09). In this work, module domain boundaries for each CCP module were considered from one residue before the first cysteine until three residues after the fourth cysteine (both inclusive).
Click directly on the CCP module to open or save the PDB file. All experimentally solved structure modules have an "EXP: " label preceding the module name. If a particular module was not modelled, a label "NO MODEL: " precedes the module name. In these cases, the link provided should take you directly to the SMART annotation for that bit of the protein sequence. Please use the labels provided as a guide, else directly check against the complete tabulated list provided above.
Non-complement human CCP module containing proteins