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 High Field


Bruker avance 800MHz
NMR Spectrometers

Currently we have four NMR spectrometers: one 800 MHz and two 600 MHz Bruker Avance, 4-channel spectrometers and one 500 MHz DMX. One of the 600 MHz spectrometers and the 800 MHz spectrometer are equipped with cryoprobes. The instruments are equipped with a range of probes, including triple-resonance, single and triple-gradient probes, and inverse- and direct-detection 5 mm probes. We also have a 600 MHz SENSY HR-MAS probe which is used for acquisition of spectra of small compounds on solid support.

The High Field NMR laboratory benefits from dedicated supervision by our NMR manager, Dr. Juraj Bella (right).

Our students and researchers also have access to the NMR service instruments of the School of Chemistry, in particular the 250 and 360 MHz Bruker instruments equipped with a sample changer.

The expertise is available to apply a wide variety 1D-4D homo- and heteronuclear methods for the determination of structures and interactions of proteins, carbohydrates and small molecules.

We will consider a limited amount of contract work. For further details please contact Dr Dusan Uhrin (left).


We are very well equipped for all aspects of manipulation of microorganisms and for expression and purification of recombinant proteins (fermenters, extensive HPLC and FPLC facilities). This includes access to many analytical systems such as protein/DNA sequencing and mass spectrometry (LC-MS, Electrospray, APCI, MALDI-TOF, Q-TOF, FTICR, FAB and EI).
For more details about some of our facilities visit the Edinburgh Protein Interaction Centre.


Computer room


As well as our NMR facilities, we are equipped for data processing, protein structure determination and modelling.

Presently we have a variety of Linux workstations, SGIs, O2's and an SGI INDIGO-2 10000, some of which were purchased with the JIF fund awarded to the Edinburgh Protein Interaction Centre. In addition, we also have a number of single and double processor Linux workstations and, with the Crystallography Department, we share a Silicon Graphics Challenge Server with six, 200MHz R10000 processors.